Coomb’s Test Negative Autoimmune Hemolytic Anemia

Direct antiglobulin ("Coombs") test-negative autoimmune hemolytic anemia: a review.

We have reviewed the literature to identify and characterize reports of warm-antibody type, autoimmune hemolytic anemia in which the standard direct antiglobulin reaction was negative but a confirmatory test indicated that the red cells were opsonized with antibody. Three principal reasons account for the absence of a positive direct antiglobulin test in these cases: a) IgG sensitization below ...

Coombs-Negative Autoimmune Hemolytic Anemia in Crohn’s Disease

BACKGROUND Anemia is a common, important extraintestinal complication of Crohn's disease. The main types of anemia in patients with Crohn's disease are iron deficiency anemia and anemia of chronic disease. Although patients with Crohn's disease may experience various type of anemia, autoimmune hemolytic anemia (AIHA) in patients with Crohn's disease, especially Coombs-negative AIHA, is very rar...

Autoimmune Hemolytic Anemia

Severe bone marrow aplasia and Coombs-positive autoimmune hemolytic anemia in microfilariasis - coincidental or causal?

Address for Correspondence: Upendra Mogalluru Srinivas, Department of Hematology, Global Hospitals, Lakdi-ka-Pul, 500004, Hyderabad, India Phone: +91 9440837561 E-mail: [email protected] A 28-year-old male presented with generalized weakness, fever, high colored urine and severe anemia, icterus and petechiae. His hemoglobin (Hb) and total leukocyte, platelet and absolute reticulocyte...

An Unusual Case of Hepatosplenic αβ T-Cell Lymphoma Presenting with Coombs'-Negative Hemolytic Anemia.

Hepatosplenic T-cell lymphoma (HSTCL) is a rare and aggressive extranodal T-cell lymphoma that comprises <5% of peripheral T-cell lymphomas. The majority of cases harbor the γδ T-cell receptor (TCR), but recently, a few cases have been shown to express the αβ TCR. Comparison of these two subtypes (αβ and γδ) shows similar clinicopathologic and cytogenetic features; however, due to the paucity o...